- Odermatt stays hot to break Swiss World Cup wins record
- Neville says Rashford's career at Man Utd nearing 'inevitable ending'
- Syria's new leader vows not to negatively interfere in Lebanon
- Germany pledges security inquest after Christmas market attack
- Putin vows 'destruction' on Ukraine after Kazan drone attack
- Understated Usyk seeks recognition among boxing legends
- France awaits appointment of new government
- Cyclone Chido death toll rises to 94 in Mozambique
- Stokes out of England's Champions Trophy squad
- Gaza rescuers say Israeli strikes kill 28
- Sweet smell of success for niche perfumes
- 'Finally, we made it!': Ho Chi Minh City celebrates first metro
- Angry questions in Germany after Christmas market attack
- China's Zheng pulls out of season-opening United Cup
- Minorities fear targeted attacks in post-revolution Bangladesh
- Tatum's 43-point triple-double propels Celtics over Bulls
- Tunisia women herb harvesters struggle with drought and heat
- Trump threatens to take back control of Panama Canal
- India's architecture fans guard Mumbai's Art Deco past
- Secretive game developer codes hit 'Balatro' in Canadian prairie province
- Large earthquake hits battered Vanuatu
- Beaten Fury says Usyk got 'Christmas gift' from judges
- First Singaporean golfer at Masters hopes 'not be in awe' of heroes
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- Stellantis backtracks on plan to lay off 1,100 at US Jeep plant
- Atletico snatch late win at Barca to top La Liga
- Australian teen Konstas ready for Indian pace challenge
- Strong quake strikes off battered Vanuatu
- Tiger Woods and son Charlie share halfway lead in family event
- Bath stay out in front in Premiership as Bristol secure record win
- Mahomes shines as NFL-best Chiefs beat Texans to reach 14-1
- Suspect in deadly Christmas market attack railed against Islam, Germany
- MLB legend Henderson, career stolen base leader, dead at 65
- Albania announces shutdown of TikTok for at least a year
- Laboured Napoli take top spot in Serie A
- Schick hits four as Leverkusen close gap to Bayern on sombre weekend
- Calls for more safety measures after Croatia school stabbings
- Jesus double lifts Christmas spirits for five-star Arsenal
- Frankfurt miss chance to close on Bayern as attack victims remembered
- NBA fines Celtics coach Mazzulla and Nets center Claxton
- Banned Russian skater Valieva stars at Moscow ice gala
- Leading try scorer Maqala takes Bayonne past Vannes in Top 14
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- Suspect in deadly Christmas market attack railed against Islam and Germany
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- Chinese ship linked to severed Baltic Sea cables sets sail
- Sorrow and fury in German town after Christmas market attack
- Guardiola vows Man City will regain confidence 'sooner or later' after another defeat
Pharma firm urged to share new 'game-changer' HIV drug
More than 300 politicians, health experts and celebrities on Thursday called for US pharmaceutical giant Gilead to allow cheap, generic versions of a promising new HIV drug to be produced so it can reach people in developing countries most affected by the deadly disease.
The drug Lenacapavir could be a "real game-changer" in the fight against HIV, according to an open letter to Gilead CEO Daniel O'Day signed by a range of former world leaders, AIDS groups, activists, actors and others.
Lenacapavir, which was approved for use in the United States and the European Union in 2022, only needs to be injected twice a year, making it particularly suited for people normally "excluded from high quality healthcare," the open letter said.
"We urge Gilead to ensure that people in the Global South living with or at risk of HIV can access this groundbreaking medicine at the same time as people in the Global North can," it added.
The signatories urged Gilead to licence the drug on the United Nations-backed Medicines Patent Pool, which would allow for cheaper generic versions to be manufactured.
Two thirds of the 39 million people living with HIV were in Africa in 2022, according to the World Health Organization. Africa also accounted for 380,000 of the 630,000 AIDS-related deaths across the world that year, the WHO figures showed.
- 'Horror and shame' -
The letter said the "world now recalls with horror and shame that it took 10 years and 12 million lives lost before generic versions" of the first antiretroviral drugs became available worldwide.
"This innovation could help end AIDS as a public health threat by 2030 – but only if all who would benefit from it can access it."
Because it only requires two shots a year, the drug could be particularly important for those who face stigma getting treated for HIV, including young women, LGBTQ people, sex workers and people who inject drugs, the letter said.
Among the signatories were former heads of state including Liberian ex-president Ellen Johnson Sirleaf and Milawi's Joyce Banda.
UNAIDS executive director Winnie Byanyima and other humanitarian figures also signed on, as did actors including Gillian Anderson, Stephen Fry, Sharon Stone and Alan Cummings.
Another signatory Francoise Barre-Sinoussi -- the French scientist who co-discovered the HIV virus -- lamented "that inequality, not science, is the greatest barrier to fighting AIDS".
On behalf of the scientists who paved the way for such new medicine, "I implore Gilead to erase much of that inequality and make a monumental step towards ending the AIDS pandemic," she said in a statement.
Lenacapavir, sold under the brand name Sunlenca, has been shown to reduce "viral load in patients with infections that are resistant to other treatments," according to the European Medicines Agency.
G.Teles--PC